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Updated: Jun 28, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Preparation and characterization of perhydroxyl-cucurbit[6]uril bonded silica stationary phase for
Si-Min Liu1, Li Xu, Cheng-Tai Wu
1Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
Abstract:
In this paper, perhydroxyl-cucurbit[6]uril ((HO)(12)CB[6]) was, for the first time, grafted to silica gel as a hydrophilic-interaction chromatographic stationary phase. Several alkaloids were used as probes to investigate the retention mechanism on the new stationary phase. The effect of mobile phase variables such as acetonitrile content, ionic strength and pH on their chromatographic behavior was investigated. The results indicate that the stationary phase behaves as a hydrophilic-interaction chromatographic packing. Finally, several alkaloids were separated on the stationary phase.
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