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Growth and nutritional aspects of infantile short bowel syndrome for the past 2 decades

Joanne F Olieman1, Dick Tibboel, Corine Penning

  • 1Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, The Netherlands. j.olieman@erasmusmc.nl

Journal of Pediatric Surgery
|October 31, 2008
PubMed

Insights

Improved care for infantile short bowel syndrome (SBS) in the 1990s led to better growth outcomes. Patients experienced shorter hospital stays and reduced parenteral nutrition (PN) duration compared to the 1980s.

Area of Science:

  • Pediatric Gastroenterology
  • Neonatal Nutrition
  • Surgical Outcomes

Background:

  • Infantile short bowel syndrome (SBS) presents significant challenges in neonatal care.
  • Nutritional management and growth monitoring are critical for improving outcomes in infants with SBS.

Purpose of the Study:

  • To characterize the first year of infantile short bowel syndrome (SBS).
  • To compare nutritional status and growth outcomes between two decades (1980s vs. 1990s).

Main Methods:

  • Retrospective analysis of pediatric patients admitted with infantile SBS between 1975 and 2002.
  • Collection of data on patient demographics, parenteral nutrition (PN) duration, enteral nutrition type, and quarterly weight and height for age.
  • Statistical comparison of outcomes between the 1980s and 1990s cohorts.

Main Results:

  • The 1990s cohort (62 patients) was larger than the 1980s cohort (28 patients).
  • Patients in the 1990s had significantly shorter lengths of stay (116 vs. 182 days) and duration of PN.
  • Mean weight-for-age SDS was significantly higher in the 1990s (0.9 SDS) compared to the 1980s.

Conclusions:

  • Advancements in care for infantile SBS improved patient outcomes in the 1990s.
  • Shorter hospital stays, reduced PN duration, and improved weight-for-age SDS were observed in the later decade.
  • Slightly longer residual bowel length in the 1990s may have contributed to better outcomes, though not statistically significant.
Abstract

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