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Published on: September 22, 2023
[A case-control study of the risk factors for fungal rhinosinusitis]
Zhuan-ping Zeng1, Ri-fang Liao, Ge-hua Zhang
1Department of Epidemiology, College of Public Health, Guangdong Pharmaceutical University, Guangzhou 510315, China. joycezzp@163.com
Objective:
To investigate the risk factors of fungal rhinosinusitis.
Methods:
The preoperative clinical data of 57 patients with a diagnosis of fungal rhinosinusitis confirmed pathologically using Gomori methenamine silver staining were analyzed statistically against the data of 57 age- and gender-matched control patients with chronic rhinosinusitis.
Results:
Compared with chronic rhinosinusitis, fungal rhinosinusitis was characterized by a significantly shorter mean disease course (37.31 months vs 130.84 months, t = 5.59, P = 0.000). The factors related to fungal rhinosinusitis included nasal mucus, purulent nasal discharge, unilateral/bilateral sinus lesion and calcified plaque in CT scan , with odds ratios of 0.17 (0.04-0.62), 0.35 (0.15-0.80), 41 (12.50-100.00) and 91 (24.01-344.95), respectively. Conditional logistic regression identified calcified plaque in CT scan as the high-risk factor of fungal rhinosinusitis.
Conclusion:
The presence of calcified plaque in CT scan indicates high risk of fungal rhinosinusitis and may serve as an important evidence for diagnosis of this disease.
Insights
Calcified plaque on CT scans is a significant risk factor for fungal rhinosinusitis, distinguishing it from chronic rhinosinusitis. This finding aids in diagnosing fungal rhinosinusitis.
Area of Science:
- Otolaryngology
- Medical Imaging
- Mycology
Context:
- Fungal rhinosinusitis presents unique diagnostic challenges.
- Distinguishing fungal rhinosinusitis from chronic rhinosinusitis is crucial for appropriate management.
Purpose:
- To identify key risk factors associated with fungal rhinosinusitis.
- To compare clinical and imaging findings between fungal rhinosinusitis and chronic rhinosinusitis.
Summary:
- A study analyzed 57 fungal rhinosinusitis patients against 57 chronic rhinosinusitis controls.
- Calcified plaque on CT scans was identified as a high-risk factor for fungal rhinosinusitis.
- Fungal rhinosinusitis showed a significantly shorter disease course compared to chronic rhinosinusitis.
Impact:
- Calcified plaque on CT scans can serve as an important diagnostic indicator for fungal rhinosinusitis.
- Understanding these risk factors can improve early detection and treatment strategies for fungal rhinosinusitis.
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