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Urinary Tract Calculi I: Introduction

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Related Experiment Video

Updated: Jun 28, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

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Published on: July 14, 2023

Sialolithiasis and primary hyperparathyroidism.

Brendan C Stack1, James G Norman

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Ark., USA. bstack@uams.edu

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|October 31, 2008
PubMed
Summary
This summary is machine-generated.

Primary hyperparathyroidism (pHPT) is linked to salivary gland stones (sialolithiasis). Patients with pHPT may develop sialolithiasis, and those with salivary stones should be evaluated for hyperparathyroidism.

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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

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Published on: August 17, 2022

Area of Science:

  • Otolaryngology
  • Endocrinology
  • Nephrology

Background:

  • Sialolithiasis, or salivary stones, commonly affects the submandibular and parotid glands.
  • Primary hyperparathyroidism (pHPT) is associated with various stone diseases, typically kidney stones.
  • The link between pHPT and sialolithiasis is infrequently reported.

Purpose of the Study:

  • To investigate the occurrence and characteristics of sialolithiasis in patients with primary hyperparathyroidism.
  • To raise awareness among otolaryngologists and parathyroid surgeons about this potential comorbidity.

Main Methods:

  • Retrospective analysis of 18 patients with sialolithiasis and pHPT.
  • Data collected from a single-specialty referral clinic focused on parathyroid surgery.
  • Descriptive statistics were used to characterize the patient cohort.

Main Results:

  • Sialolithiasis was identified in 18 out of 3,000 patients undergoing parathyroid surgery.
  • Demographics and specific characteristics of sialolithiasis in the context of pHPT were described.

Conclusions:

  • Sialolithiasis can be a comorbidity of primary hyperparathyroidism.
  • Parathyroid surgeons should consider sialolithiasis in pHPT patients.
  • Practitioners should consider pHPT as a potential cause of salivary gland stones.