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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

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Propagation of the Microsporidian Parasite Edhazardia aedis in Aedes aegypti Mosquitoes
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Dermatophyte infections in Cairo, Egypt.

S M Zaki1, N Ibrahim, K Aoyama

  • 1Microbiology Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt. shzaki@yahoo.com.

Mycopathologia
|October 31, 2008
PubMed
Summary

This study investigated dermatophyte infections in Cairo, finding tinea capitis most common. Trichophyton violaceum was the predominant species identified in patients.

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Published on: June 13, 2018

Area of Science:

  • Medical Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Dermatophytoses are superficial fungal infections affecting skin, hair, and nails.
  • Accurate etiological diagnosis is crucial for effective treatment and public health management.
  • Limited data exists on the prevalence and etiological agents of dermatophytoses in Egypt.

Purpose of the Study:

  • To identify the prevalence of dermatophyte infections.
  • To determine the etiological agents responsible for these infections.
  • To characterize the clinical patterns of dermatophytoses in a referred patient population in Cairo.

Main Methods:

  • Clinical diagnosis of dermatophytoses in 506 referred patients.
  • Macroscopic and microscopic examination for species identification.
  • Sequencing of the internal transcribed spacer (ITS1-5.8S-ITS2) rDNA region for confirmation.

Main Results:

  • 403 patients (79.6%) were diagnosed with dermatophytoses.
  • Tinea capitis was the most prevalent clinical diagnosis (76.4%).
  • Trichophyton violaceum was the most frequently isolated species (71.1%), followed by Microsporum canis (21.09%).

Conclusions:

  • Dermatophyte infections, particularly tinea capitis, are common in the studied Egyptian population.
  • Trichophyton violaceum is the leading cause of dermatophytophytosis in this region.
  • Molecular identification methods confirm traditional diagnostic techniques for etiological agents.