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Disclosure issues in neuroscience research
Lisa S Parker1, Michelle L Kienholz
1Center for Bioethics and Health Law, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. lisap@pitt.edu
Accountability in Research
|October 31, 2008
Summary
Neuroscientific research requires clear informed consent regarding incidental findings and study results. Addressing disclosure expectations manages subject expectations and study risk-benefit balance.
Area of Science:
- Neuroscience
- Bioethics
Background:
- Disclosure of incidental findings and research results presents ethical challenges in neuroscientific studies.
- These disclosures can create subject expectations and impact the risk-benefit analysis of research.
Purpose of the Study:
- To examine disclosure issues in neuroscientific research, focusing on informed consent.
- To provide recommendations for managing incidental findings and research result disclosures.
Main Methods:
- Literature review on ethical considerations in neuroscientific research disclosure.
- Analysis of informed consent processes in the context of potential findings.
Main Results:
- Disclosure issues are integral to informed consent in neuroscientific research.
- Potential for disclosure impacts subject expectations and the study's risk-benefit ratio.
Conclusions:
- Informed consent processes must proactively address the disclosure of incidental findings and research results.
- Clear guidelines are needed for when information will be offered, withheld, and how subjects will be supported in understanding disclosed information.
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