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Updated: Jun 28, 2026

Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
Published on: February 8, 2016
[Sertoli cell malignant tumor]
Igor Azurmendi Arín1, Roberto Llarena Ibarguren, Jorge García-Olaverri Rodríguez
1Servicio de Urología, Hospital de Cruces, Bilbao, Vizcaya, España. igorazurmendi@hotmail.com
Objective:
We report a new case of Sertoli cell testicular tumor with malignant characteristics.
Methods:
77 year-old male patient, suffering a general wasting syndrome presenting with a left solid testicular mass with the diagnosis of malignant Sertoli cell tumor after orchyectomy, without local, regional or distant dissemination, and a benign outcome after 18 months of follow-up.
Results:
Sertoli cell tumor or androblastoma is classified as non-germ cell tumor derived from the stroma of the sexual cords. There are three types depending on its cellular composition: calcified big cell, sclerotic cell, and the most frequent of all, the classic type.
Conclusions:
Being the Sertoli cell testicular tumor rare, its malignant type is even rarer, accounting for not more than 10% of all. Despite the pathological characteristics related to malignancy, its posterior behaviour is unpredictable and not much known, the some than follow-up and treatment, because it is not sensible to cytostatic drugs. The existence of metastases continues to be the only valid parameter with prognostic value.
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