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[Study on the effect of phloretin on inhibiting malignant pheotype of BEL-7402 cells]
Hui Luo1, Ya-Jun Wang, Jie Chen
1Department of Chemistry, Guangdong Medical College, Zhanjiang 524023, China. luohui@gdmc.edn.cn
Objective:
To investigate the effect of phloretin on inhibiting BEL-7402 cells' growth, invasive, migration and adhesion ability and the rate of colony formation.
Methods:
BEL-7402 cells' growth, invasive, migration and adhesion ability and the rate of colony formation were examined with MIT method and Costar Transwell.
Results:
Phloretin inhibited the growth, invasive, migration and adhesion ability of BEL-7402 cells and reduced the rate of colony formation in dose-dependent.
Conclusion:
Phloretin can inhibit BEL-7402 cells' malignant pheotype.
