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Related Concept Videos

Muscle Coordination and Action01:24

Muscle Coordination and Action

Muscle coordination is a complex and finely tuned process essential for smooth and purposeful movements like flexion, extension, adduction, abduction, and rotation. The human body orchestrates the actions of various muscles working in concert, each with a specific role. Four functional types describe how muscles work together: agonist, antagonist, synergist, and fixator.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement.

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Related Experiment Video

Updated: Jun 28, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
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Dexterous movement complexity and cerebellar activation: a meta-analysis.

Raymond C K Chan1, Jia Huang, Xin Di

  • 1Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. rckchan@psych.ac.cn

Brain Research Reviews
|November 1, 2008
PubMed
Summary

The cerebellum

Area of Science:

  • Neuroscience
  • Motor Control
  • Neuroimaging

Background:

  • Lesion studies confirm the cerebellum's role in movement coordination.
  • Understanding consistent cerebellar activation across motor task complexities remains unclear.
  • Specific cerebellar contributions to finger coordination in dexterous tasks require further investigation.

Purpose of the Study:

  • To review imaging studies on cerebellar activation during motor tasks.
  • To investigate consistent cerebellar activation across varying motor task complexities.
  • To identify specific cerebellar regions involved in finger coordination during dexterous manipulation.

Main Methods:

  • Review of neuroimaging studies in healthy subjects.
  • Mini meta-analysis using label-based methods.

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  • Activation Likelihood Estimation (ALE) analysis.

    • Main Results:

    • Consistent activation observed in ipsilateral anterior and vermis regions of the cerebellum.
    • These cerebellar regions are associated with finger and hand movements.
    • Activation patterns varied with different levels of motor task complexity.

    Conclusions:

    • The ipsilateral anterior cerebellum and vermis are consistently involved in dexterous motor tasks.
    • These findings clarify the cerebellum's role in complex finger movements.
    • Neuroimaging provides insights into the functional localization within the cerebellum for motor control.