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Lack of specific saxitoxin binding to rat mast cells
M R Vieytes1, M C Louzao, M J Bujan
1Departmentos de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Santiago de Compostela, Lugo, Spain.
Abstract:
We studied whether or not mast cells are endowed with specific sodium channels, by using tritiated saxitoxin which binds to site 1 of sodium channels on excitable tissues. Our results suggest that rat pleural and peritoneal mast cells lack specific sodium channels.