Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Initiation of Translation

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...

Initiation of Translation

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...

The Spindle Assembly Checkpoint

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...

The Spindle Assembly Checkpoint

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...

The Availability Heuristic

The Availability Heuristic

A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):

Upward Impending Motion

Upward Impending Motion

A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. Its operation is based on converting the force applied at its handle into a torsional moment, causing the upward impending motion of the screw. This movement is accomplished by overcoming the static friction between the threads of the screw and the jack.
To better comprehend how a screw jack functions, consider the completely unraveled thread as a block in contact with the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gender differences in the symptoms of major depressive disorder.

The Journal of nervous and mental disease·2007

Same author

Neuroendocrine challenge with a 5-HT(1D) receptor agonist differentiates between two subtypes of bipolar disorder according to polarity of onset.

Journal of psychopharmacology (Oxford, England)·2005

Same author

A review of acute treatments for bipolar depression.

International clinical psychopharmacology·2004

Same author

Growth hormone and prolactin response to apomorphine in bipolar and unipolar depression.

Journal of affective disorders·2003

Same author

Deep white matter hyperintensities in patients with bipolar depression, unipolar depression and age-matched control subjects.

Bipolar disorders·2003

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

Published on: May 5, 2023

What are we waiting for?

Trevor Silverstone¹

¹Department of Psychiatry, University of Toronto, Canada.

Healthcarepapers

|November 1, 2008

Summary

This summary is machine-generated.

Addressing the obesity epidemic requires careful consideration of public policy and intervention effectiveness. Long-term strategies are essential for sustainable weight management, as losing weight is a slow process.

More Related Videos

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Published on: June 16, 2021

Related Experiment Videos

Last Updated: Jun 28, 2026

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

Published on: May 5, 2023

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Published on: June 16, 2021

Area of Science:

Public Health
Health Policy
Obesity Research

Background:

The current obesity epidemic presents a significant public health challenge.
Interventions and public policy are critical components of obesity management.
Diverse perspectives exist on the most effective approaches to combatting obesity.

Discussion:

Examines the challenges in identifying promising obesity interventions.
Offers perspectives on the interrelationships between policy and epidemic management.

Key Insights:

Effective obesity management necessitates a long-term perspective.
The difficulty lies in selecting interventions with proven efficacy.

Outlook:

Future strategies must integrate policy with evidence-based interventions.
Sustainable weight loss requires a patient and persistent approach.