Related Experiment Video
Updated: Aug 4, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Dietary risk factors associated with acute and persistent diarrhea in children in Karachi, Pakistan
S H Badruddin1, A Islam, K M Hendricks
1Department of Medicine/Community Health Science, Aga Khan Medical College, Karachi, Pakistan.
Insights
Feeding practices significantly impact childhood diarrhea in Pakistan. Delayed breastfeeding and increased supplemental milk intake were identified as key risk factors for both acute and persistent diarrhea in young children.
Area of Science:
- Pediatrics
- Public Health
- Nutrition
Background:
- Diarrheal diseases pose a significant threat to child health in developing nations.
- Feeding practices are suspected to influence the incidence and severity of diarrheal diseases.
Purpose of the Study:
- To evaluate the association between infant feeding practices and diarrheal diseases in young children.
- To identify specific feeding behaviors that may act as risk factors for acute diarrhea and persistent diarrhea.
Main Methods:
- A comparative study involving three groups of male children aged 6-36 months in Karachi, Pakistan.
- Groups included children with persistent diarrhea (n=100), acute diarrhea (n=79), and a comparison group (n=86).
- Data collected on feeding practices, socioeconomic status, and maternal literacy.
Main Results:
- Over 95% of infants were breast-fed, but delayed initiation was more prevalent in children with diarrhea.
- Children with persistent diarrhea (92%) and acute diarrhea (87%) were more likely to receive supplemental milk compared to the comparison group (69%).
- Maternal literacy rates were significantly higher in the comparison group.
Conclusions:
- Specific feeding practices, including delayed breastfeeding and increased supplemental milk consumption, are associated with an increased risk of diarrheal diseases in children.
- These findings highlight the importance of targeted nutritional interventions and education to reduce childhood diarrhea in Pakistan.
Abstract:
Feeding practices may have an important impact on diarrheal diseases in developing countries. This study evaluated feeding practices in three groups of male children aged 6-36 mo: 100 with persistent diarrhea (PD), 79 with acute diarrhea (AD), and 86 in a comparison group (CG). The children came from comparably poor socioeconomic settings in Karachi, Pakistan, except that the literacy rates were higher in mothers of the CG (P = 0.0001). Although greater than 95% of all infants were breast-fed, delayed initiation of breast-feeding was more common in the diarrhea groups. Children with diarrhea were also more likely to receive supplemental milk (PD = 92%, AD = 87%) than were children in the CG (69%, P less than 0.05). Feedings were not withheld during diarrhea but changes were made in the nature of foods given. These results indicate that several feeding practices may be important risk factors for diarrhea in Pakistan.
Related Concept Videos
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Bacterial Gastroenteritis
Cholera
Giardiasis

