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Updated: Jun 28, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Intracranial epidermoid--a 10-year study.

Kaushik Roy1, Asis Kumar Bhattacharyya, P Tripathy

  • 1Department of Neurosurgery, Bangur Institute of Neurology, Kolkata 700025.

Journal of the Indian Medical Association
|November 4, 2008
PubMed
Summary
This summary is machine-generated.

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Intracranial epidermoid tumors are rare, with cerebellopontine angle and fourth ventricle being common locations. Surgical removal offers satisfactory outcomes, though complications like chemical meningitis can occur.

Area of Science:

  • Neurosurgery
  • Neurology
  • Neuroradiology

Background:

  • Intracranial epidermoid cysts are congenital tumors, often presenting with neurological deficits based on location.
  • These tumors are typically slow-growing and can reach significant sizes before diagnosis.

Purpose of the Study:

  • To analyze the clinical presentation, surgical management, and outcomes of intracranial epidermoid tumors.
  • To evaluate the diagnostic accuracy of CT scans and the incidence of postoperative complications.

Main Methods:

  • Retrospective review of 28 patients with intracranial epidermoid tumors operated over 10 years.
  • Analysis of patient demographics, tumor location, presenting symptoms, diagnostic methods, surgical approaches, and outcomes.

Main Results:

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  • Common locations included the cerebellopontine angle (n=15) and fourth ventricle (n=6).
  • Presenting symptoms varied by location, with hearing loss/vertigo common in CPA and gait disturbances in fourth ventricle tumors.
  • CT scan was diagnostic in 23 cases; 16 patients had ventriculomegaly requiring shunting.
  • Total removal was achieved in 6, near-total in 14, and partial in 8 cases. Five patients died, and complications included chemical meningitis (7) and worsened neurological deficits (5).

Conclusions:

  • Surgical management of intracranial epidermoids can yield satisfactory outcomes with appropriate treatment.
  • Early diagnosis and surgical intervention are crucial for managing these tumors and preventing long-term deficits.
  • While surgical risks exist, most complications are manageable, and long-term follow-up indicates good prognosis for most patients.