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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...

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Updated: Jun 28, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Giant retroperitoneal liposarcoma.

Angel Herrera-Gómez1, César Ortega-Gutiérrez, Alejandro Mohar Betancourt

  • 1Department of Surgical Oncology, Instituto Nacional de Cancerología, México, D.F., Mexico.

World Journal of Surgical Oncology
|November 4, 2008
PubMed
Summary
This summary is machine-generated.

Giant retroperitoneal liposarcoma treatment can be challenging. Surgical intervention, even after palliative chemotherapy failure, may lead to successful outcomes and prolonged disease-free survival in select cases.

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Last Updated: Jun 28, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Area of Science:

  • Oncology
  • Surgical Oncology
  • Soft Tissue Sarcomas

Background:

  • Retroperitoneal liposarcoma is the most common soft tissue sarcoma in this anatomical location.
  • Complete surgical resection is the established gold standard for treating liposarcoma.
  • Management of unresectable or recurrent retroperitoneal liposarcomas presents significant challenges.

Observation:

  • A case of a 24-year-old male with a giant retroperitoneal liposarcoma is presented.
  • The patient initially received palliative chemotherapy due to non-resectable tumor status.
  • Systemic treatment provided no demonstrable benefit, prompting a reassessment of surgical options.

Findings:

  • Complete macroscopic tumor resection was achieved without the need for multi-organ resection.
  • The patient remains alive and disease-free at 14 months post-operatively.
  • This case highlights the potential for surgical success even after neoadjuvant chemotherapy failure.

Implications:

  • Aggressive surgical approaches, including re-exploration for recurrences, may be necessary for retroperitoneal liposarcomas.
  • Surgical resectability should be evaluated based on individual patient tolerance and potential for symptom palliation.
  • Careful consideration of the balance between surgical morbidity and the likelihood of achieving prolonged survival is crucial.