Related Experiment Video
Updated: Jun 28, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
[Air embolism on central venous access in a premature neonate, beware of the infusion device assembly! ]
G Thiriez1, M-H Choulet, S Felix
1Service de pédiatrie 2, CHU Saint-Jacques, 2, place Saint-Jacques, 25030 Besançon, France. gerard.thiriez@univ-fcomte.fr
Abstract:
A fatal pulmonary air embolism, confirmed by an oriented necropsy, is described in a 25-day-old premature and small-for-gestational-age neonate. The embolism was suspected after air bubbles were detected in the infusion line. The air bubbles originated from a male Luer-lock to male Luer-lock connector, which was part of a specific assembly of the perfusion line. A solution to this problem is thereby proposed. We recommend caution in using complex infusion line assemblies because such complications are probably underestimated.
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