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Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis II: Pathophysiology

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

Acute Pancreatitis II: Clinical Manifestations and Management

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...

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Updated: Jun 28, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Pancreatitis in pregnancy.

Jennifer J Eddy¹, Mark D Gideonsen, Jonathan Y Song

¹University of Wisconsin School of Medicine and Public Health, Department of Family Medicine, Eau Claire, Wisconsin 54703, USA. jjemdg@sbcgolbal.net

Obstetrics and Gynecology

|November 4, 2008

Summary

Pancreatitis in pregnancy is rare, affecting about 1 in 3,000 deliveries. Biliary causes are common and linked to better outcomes, while non-biliary causes indicate higher risks for adverse pregnancy events.

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Last Updated: Jun 28, 2026

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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection

Published on: May 10, 2024

Area of Science:

Obstetrics and Gynecology
Gastroenterology
Perinatology

Background:

Pancreatitis during pregnancy is uncommon but carries potential risks.
Understanding its causes and complications is crucial for maternal and fetal well-being.

Purpose of the Study:

To determine the incidence, causes, and complications of pancreatitis in pregnant individuals.
To identify factors associated with adverse outcomes in these cases.

Main Methods:

A retrospective chart review was conducted.
Data from 101 pregnant patients diagnosed with pancreatitis between 1992 and 2001 across 15 hospitals were analyzed.

Main Results:

The incidence of pancreatitis in pregnancy was 1 in 3,021 deliveries.
Acute pancreatitis, often biliary in origin, had better outcomes than non-biliary causes.
Alcohol-induced pancreatitis was associated with increased recurrence and preterm delivery rates.

Conclusions:

Pancreatitis is a rare obstetric complication, with most cases being acute and gallstone-related.
Non-biliary causes of pancreatitis in pregnancy warrant close attention due to associated adverse outcomes.