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Related Experiment Video

Updated: Jun 28, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

Laryngeal candidiasis mimicking malignancy.

Fabio P Nunes¹, Todd Bishop, Manju L Prasad

¹Department of Medicine, University of Massachusetts, Worcester, Massachusetts 01655, USA.

The Laryngoscope

|November 4, 2008

Summary

This summary is machine-generated.

Isolated laryngeal candidiasis is rare in healthy individuals. This case highlights a rare instance mimicking cancer in a patient using inhaled steroids, successfully treated with antifungal medication.

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Last Updated: Jun 28, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

Area of Science:

Otolaryngology
Infectious Diseases
Pulmonology

Background:

Laryngeal candidiasis is uncommon in immunocompetent individuals, with limited reported cases.
Secondary laryngeal candidiasis from inhaled steroids typically presents mildly, affecting 10-15% of users with dysphonia.
Chronic obstructive pulmonary disease (COPD) management often involves inhaled corticosteroids.

Observation:

A case of laryngeal candidiasis mimicking laryngeal carcinoma is presented.
The patient was immunocompetent and receiving inhaled fluticasone for COPD.
The lesion presented as a malignancy on initial assessment.

Findings:

Biopsy confirmed the absence of malignancy.
The condition was diagnosed as laryngeal candidiasis.
The patient showed a positive response to oral fluconazole treatment.

Implications:

This case underscores the importance of considering laryngeal candidiasis in the differential diagnosis of laryngeal lesions, even in immunocompetent patients.
It highlights a rare but serious presentation of inhaled corticosteroid-induced candidiasis.
Early diagnosis and appropriate antifungal treatment are crucial for favorable outcomes.