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Updated: Jun 28, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Sheet-beam geometry for in vivo fluorescent x-ray computed tomography: proof-of-concept experiment in molecular
Qingkai Huo1, Tetsuya Yuasa, Takao Akatsuka
1Yamagata University, Yonezawa, Yamagata, Japan.
Abstract:
We propose a fluorescent x-ray computed tomography method using an array of detectors with an incident sheet beam, aimed at providing molecular imaging with high sensitivity and good spatial resolution. In this study, we prove the feasibility of this concept and investigate its imaging properties, including spatial and contrast resolutions and quantitativeness, by imaging an acrylic phantom and a normal mouse brain using a preliminary imaging system with monochromatic synchrotron x rays.
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