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Updated: Jun 28, 2026

PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
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[Fluorquinolone associated tendon rupture].

A Rätz Bravo1, R Stoll, P Bürr

  • 1Klinische Pharmakologie and Toxikologie, Departement Innere Medizin, Universitätsspital Basel, Basel. raetza@uhbs.ch

Praxis
|November 4, 2008
PubMed
Summary
This summary is machine-generated.

A 38-year-old experienced an Achilles tendon rupture after exercise, shortly after taking ciprofloxacin for chlamydial urethritis. This case highlights a potential link between fluoroquinolone antibiotics and tendon injuries.

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PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
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Area of Science:

  • Orthopedics
  • Pharmacology
  • Sports Medicine

Background:

  • Achilles tendon ruptures are serious injuries often associated with physical activity.
  • Antibiotic use, particularly fluoroquinolones, has been anecdotally linked to tendon pathologies.

Observation:

  • A 38-year-old male presented with a right Achilles tendon rupture following physical exertion.
  • The patient had recently completed a course of ciprofloxacin (500mg twice daily) for chlamydial urethritis.

Findings:

  • The temporal association suggests a possible role of ciprofloxacin in the Achilles tendon rupture.
  • This case warrants further investigation into the fluoroquinolone class and tendon integrity.

Implications:

  • Clinicians should consider antibiotic-induced tendinopathy in patients presenting with tendon ruptures.
  • Further research is needed to elucidate the mechanism and prevalence of fluoroquinolone-associated tendon damage.