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Updated: Jun 28, 2026

Flow Cytometry-based Assay for the Monitoring of NK Cell Functions
Published on: October 30, 2016
Killers and beyond: NK-cell-mediated control of immune responses
Christopher E Andoniou1, Jérôme D Coudert, Mariapia A Degli-Esposti
1The University of Western Australia, Western Australia, Australia.
Abstract:
Effective immunity requires coordinated activation of innate and adaptive immune responses. NK cells are principal mediators of innate immunity, able to respond to challenge quickly and generally without prior activation. The most acknowledged functions of NK cells are their cytotoxic potential and their ability to release large amounts of cytokines, especially IFN-gamma. Recently, it has become clear that NK cells are more than assassins. Indeed, NK cells play critical roles in shaping adaptive immunity.
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