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Updated: Jun 28, 2026

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
Renal cell carcinoma with rhabdoid features. Divergent differentiation of conventional (clear cell) carcinoma
1Department of Pathology, 3rd Hospital of Social Insurance Institute, and Athens University School of Medicine, Athens, Greece.
Abstract:
A rare case of renal cell carcinoma (RCC) with rhabdoid features in an adult man is presented. This tumor with rhabdoid features, also known as composite neoplasm, represents a pattern of progression emerging from specific histologic RCC types. RCC with rhabdoid features is a highly aggressive neoplasm and its malignant behavior may be due to the high-cell proliferation activity of the rhabdoid areas. Rhabdoid features in RCC may represent a final pathway of differentiation in clonal progression to a high-grade, aggressive biologic state.
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