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Updated: Jun 28, 2026

Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
Published on: September 18, 2011
[Advances of cell transplantation for treating intervertebral disc degeneration]
1Department of Orthopaedics, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, PR China.
Objective:
To introduce the research of cell transplantation for treating intervertebral disc degeneration.
Methods:
The original articles in recent years about cell transplantation for treating intervertebral disc degeneration were extensively reviewed, and retrospective and comprehensive analysis was performed.
Results:
Transplantation of intervertebral disc-derived cells or BMSCs by pure cell transplantation or combined with collagen scaffold into intervertebral disc could express nucleus pulposus-like phenotype. All the cells transplanted into intervertebral disc could increase extracellular matrix synthesis and relieve or even inhibit further intervertebral disc degeneration.
Conclusion:
Cell transplantation for treating intervertebral disc degeneration may be a promising approach.
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