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Updated: Jun 28, 2026

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
Published on: January 31, 2013
Eccentric exercises; why do they work, what are the problems and how can we improve them?
J D Rees1, R L Wolman, A Wilson
1Defence Medical Rehabilitation Centre, Headley Court, near Epsom, Surrey, KT18 6JW, UK. j.rees@doctors.org.uk
Eccentric exercises (EE) effectively manage chronic tendinopathies like Achilles and patellar. Further research is needed to optimize EE protocols for greater efficacy and patient adherence.
Area of Science:
- Sports Medicine
- Rehabilitation Science
- Orthopedic Research
Background:
- Eccentric exercises (EE) are established treatments for chronic tendinopathies, particularly Achilles and patellar.
- Current EE protocols face challenges including time commitment and patient motivation.
- The efficacy of EE varies depending on the specific tendinopathy and lesion location.
Purpose of the Study:
- To review the current understanding of eccentric exercises in tendinopathy management.
- To identify limitations and unanswered questions regarding EE protocols.
- To explore emerging evidence on the mechanisms and optimization of EE.
Main Methods:
- Review of existing literature on eccentric exercises for tendinopathy.
- Analysis of controlled trials and in vivo studies.
- Discussion of clinical observations and emerging research findings.
Main Results:
- EE demonstrate success in controlled trials for specific tendinopathies.
- Efficacy is influenced by lesion location, with insertional Achilles tendinopathy being less responsive.
- New insights into the effects of EE on tendinopathic tissue are emerging.
- In vivo studies offer potential explanations for the therapeutic benefits of EE over concentric exercises.
Conclusions:
- While effective, standard EE protocols require optimization for time and patient adherence.
- Further research is crucial to enhance the effectiveness of EE for diverse tendinopathies.
- Understanding the underlying mechanisms of EE is key to developing improved therapeutic strategies.
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