Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

TACE plus donafenib and immune checkpoint inhibitors for intermediate HCC (CHANCE2410 study): a propensity score matching analysis.

European radiology experimental·2026

Same author

Precision transarterial chemoembolization in hepatocellular carcinoma: patient selection, standardized techniques, and quantitative evaluation.

Hepatobiliary surgery and nutrition·2026

Same author

HOXD11-NMDAR signaling drives neuroendocrine prostate cancer and enables potential therapeutic intervention as a target of memantine.

Cell reports·2026

Same author

Impact of Procedural Quality on Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma: A Multicenter Study.

Liver cancer·2026

Same author

Camrelizumab and Apatinib With or Without Transarterial Chemoembolisation as First-Line Treatment for Advanced Hepatocellular Carcinoma.

Alimentary pharmacology & therapeutics·2026

Same author

Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes.

Gut·2026

Same journal

The Prognostic Value of <sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG PET/CT in Metastatic Castration-Resistant Prostate Cancer Treated with <sup>177</sup>Lu-EB-PSMA.

Annals of nuclear medicine·2026

Same journal

Atomic degradation: chemical design strategies and immunotherapeutic mechanisms of radio-PROTACs.

Annals of nuclear medicine·2026

Same journal

Impact of biguanide therapy on hepatic <sup>18</sup>F-fluorodeoxyglucose-positron emission tomography quantitative parameters in patients with diabetes: a dynamic positron emission tomography study.

Annals of nuclear medicine·2026

Same journal

Dual-time-point 68Ga-FAPI PET/CT in gastrointestinal malignancies: head-to-head comparison with 18 F-FDG for lesion detection and patient-level assessment.

Annals of nuclear medicine·2026

Same journal

Bloodpool SPECT/CT offers enhanced sensitivity for the diagnosis of frozen shoulder.

Annals of nuclear medicine·2026

Same journal

Adsorption treatment of <sup>177</sup>Lu radioactive wastewater with <sup>177m</sup>Lu impurity: batch versus column methods.

Annals of nuclear medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

Internal radiotherapy using 32P colloid or microsphere for refractory solid tumors.

Wen Gao¹, Lu Liu, Gao-Jun Teng

¹Nuclear Medicine Technology Institution of Clinical Medical, College of Southeast University, 87 Dinjiaqiao, Nanjing, Jiangsu, 210009, China.

Annals of Nuclear Medicine

|November 5, 2008

Summary

This summary is machine-generated.

Radioactive 32P colloids or microspheres effectively treated refractory solid tumors, showing a 93.4% inhibition rate and significant survival benefits. Most patients experienced complete or partial remission with minimal side effects.

More Related Videos

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Related Experiment Videos

Last Updated: Jun 28, 2026

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Area of Science:

Oncology
Radiology
Nuclear Medicine

Background:

Refractory solid tumors present significant treatment challenges.
Palliative and curative treatment options are limited for advanced stages.

Purpose of the Study:

To evaluate the efficacy of 32P colloids or microspheres in treating refractory solid tumors.
To assess outcomes following arterial interventional administration or stromal injection of 32P agents.

Main Methods:

60 patients with refractory solid tumors received 32P microspheres or radioactive colloid via arterial intervention or stromal injection.
Administration guided by imaging (CT, X-ray, ultrasonogram) or direct surgical vision.
Tumor inhibition, side effects, and survival were monitored.

Main Results:

A 93.4% tumor inhibition rate was observed.
Complete remission in 51.7% and partial remission in 41.7% of patients.
Average survival was 35 months, with one patient surviving 90 months; minimal side effects reported.

Conclusions:

Arterial interventional administration or stromal injection of 32P microspheres/colloid is effective for refractory solid tumors.
Safe dosage ranges established for 32P glass microspheres (555-740 MBq) and 32P chromic phosphate (185-370 MBq).