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Updated: Jun 28, 2026

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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Novel technologies for natural orifice surgery: an overview
Tahar Benhidjeb1, Jens Burghardt, Michael Stark
1Department of General, Charité - Universitätsmedizin Berlin, Berlin, Germany. mail: tahar.benhidjeb@charite.de
Summary
Natural Orifice Surgery (NOS) uses body
Area of Science:
- Minimally Invasive Surgery
- Surgical Technology
- Gastroenterology
Background:
- Natural Orifice Surgery (NOS) aims to simplify and enhance the safety of abdominal procedures.
- NOS utilizes existing bodily orifices to introduce surgical instruments, avoiding abdominal wall penetration.
- Common NOS approaches include transvaginal and transgastric routes for human applications.
Purpose of the Study:
- To provide an overview of current techniques and technologies in Natural Orifice Surgery.
- To highlight advancements and challenges in NOS procedures.
Main Methods:
- Review of existing literature and development of surgical prototype devices for NOS.
- Analysis of transvaginal and transgastric approaches for transluminal access and closure.
Main Results:
- The transvaginal approach is noted for its simplicity and safety, requiring no complex closure devices.
- Significant obstacles remain in achieving safe and effective transluminal access and closure for the transgastric approach.
- Various prototype devices are under development to address transgastric NOS challenges.
Conclusions:
- Natural Orifice Surgery offers a safer alternative to traditional abdominal surgery.
- Further technological development is crucial for overcoming challenges in transgastric Natural Orifice Surgery.
- Continued research in NOS techniques and devices promises to advance minimally invasive surgical options.

