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Related Experiment Video

Updated: Jun 28, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

Smoking cessation in pregnancy.

Craig Rore¹, Vicki Brace, Peter Danielian

¹Aberdeen Royal Infirmary, Medicines Information, Department of Pharmacy, Foresterhill, Aberdeen AB25 2ZN, UK. craig.rore@nhs.net

Expert Opinion on Drug Safety

|November 6, 2008

Summary

Nicotine replacement therapy (NRT) is the preferred method for helping pregnant women quit smoking. Its safety in pregnancy is more established than other smoking cessation aids, protecting both mother and baby.

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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

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Published on: August 25, 2014

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Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

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Published on: February 28, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Area of Science:

Obstetrics and Gynecology
Addiction Medicine
Public Health

Background:

Smoking during pregnancy poses significant risks to fetal development and maternal health.
Managing smoking cessation in pregnant women presents challenges due to pharmacotherapy safety concerns.
Various smoking cessation aids exist for non-pregnant individuals, including NRT, bupropion, varenicline, and non-drug therapies.

Purpose of the Study:

To offer guidance to healthcare providers on effective smoking cessation management for pregnant patients.
To review the risks and efficacy of different smoking cessation approaches in pregnancy.

Main Methods:

A comprehensive literature search was conducted.
Original studies investigating the safety and efficacy of smoking cessation methods in pregnancy were identified.

Main Results:

Nicotine replacement therapy (NRT) is identified as the primary choice for smoking cessation in pregnant individuals.
The safety of alternative smoking cessation therapies during pregnancy remains unproven.

Conclusions:

Nicotine replacement therapy (NRT) is recommended as the agent of choice for smoking cessation in pregnant women.
Further research is needed to establish the safety and efficacy of other pharmacotherapies in this population.