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Updated: Jun 28, 2026

04:19
The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Hard tissue alterations after socket preservation: an experimental study in the beagle dog
Stefan Fickl1, Otto Zuhr, Hannes Wachtel
1Private Institute for Periodontology and Implantology, Munich, Germany. fickl@ipi-muc.de
Clinical Oral Implants Research
|November 6, 2008
Summary
Socket preservation using BioOss Collagen showed limited impact on vertical bone loss but aided horizontal bone regeneration. Mechanical stability from BioOss Collagen and grafts may prevent soft tissue collapse.
Area of Science:
- Periodontology
- Dental Implantology
- Bone Regeneration
Background:
- Socket preservation is crucial for maintaining alveolar ridge dimensions after tooth extraction.
- Various materials and techniques are employed to minimize post-extraction bone resorption.
- BioOss Collagen is a commonly used bone substitute in dental procedures.
Purpose of the Study:
- To evaluate the effects of different socket preservation techniques on vertical and horizontal bone dimensions.
- To compare BioOss Collagen alone versus BioOss Collagen with a free gingival graft versus an empty socket control.
Main Methods:
- Extraction of premolar teeth in beagle dogs without flap elevation.
- Socket treatment groups: BioOss Collagen with sutures, BioOss Collagen with a gingival graft, and blood clot with sutures (control).
- Histometric analysis of vertical bone loss and horizontal bone dimensions at 4 months post-extraction.
Main Results:
- Mean vertical bone loss was comparable across all groups (2.8-3.3 mm).
- Horizontal bone dimensions showed significant differences, particularly at 1 mm apical to the crest (P<0.001), with BioOss Collagen groups performing better than the control.
- BioOss Collagen with a graft showed slightly better horizontal dimensions than BioOss Collagen alone (P<0.05).
Conclusions:
- BioOss Collagen incorporation has a limited effect on vertical bone dimension but promotes horizontal bone regeneration.
- The mechanical stability provided by BioOss Collagen, potentially enhanced by a gingival graft, may prevent soft tissue collapse and aid bone preservation.

