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Mammalian cartilage synthesizes both proteoglycan and non-proteoglycan forms of type IX collagen
S Ayad1, A Marriott, V H Brierley
1Department of Biochemistry and Molecular Biology, University of Manchester Medical School, U.K.
The Biochemical Journal
|September 1, 1991
Abstract:
Bovine epiphysial cartilage synthesizes both proteoglycan (PG) and non-PG forms of type IX collagen in a ratio of approx. 2:1. The PG form with its attached glycosaminoglycan on the alpha 2(IX) chain is the major form in the medium, whereas both forms are found in the tissue. The results are discussed with regard to cartilage matrix organization.