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Related Concept Videos

Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...
Articulations of the Vertebral Column01:28

Articulations of the Vertebral Column

In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

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Related Experiment Video

Updated: Jun 28, 2026

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
08:46

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Published on: March 24, 2020

[Hemifacial spasms and vertebral dolichoectasias].

M Arantes1, R Garcia, J R Pereira

  • 1Servicio de Neurorradiología, Hospital Pedro Hispano, Matosinhos, Portugal. mavildearantes@hotmail.com

Revista De Neurologia
|November 6, 2008
PubMed
Summary

Vertebral artery dolichoectasia can cause hemifacial spasm (HFS) by compressing the facial nerve. Advanced imaging like MRI and MRA are crucial for diagnosing this rare cause of HFS.

Area of Science:

  • Neurology
  • Neurosurgery
  • Radiology

Background:

  • Hemifacial spasm (HFS) involves involuntary facial muscle contractions on one side.
  • It typically results from facial nerve irritation, often due to vascular compression at the brainstem.

Observation:

  • Three cases of HFS were identified with vertebral artery dolichoectasia.
  • This condition involved enlarged, elongated vertebral arteries compressing the facial nerve.

Findings:

  • Magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) revealed vertebral dolichoectatic arteries.
  • These findings confirmed the vascular compression as the cause of HFS in these patients.

Implications:

  • MRI and MRA are essential for diagnosing vertebral artery dolichoectasia causing HFS.

Related Experiment Videos

Last Updated: Jun 28, 2026

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
08:46

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Published on: March 24, 2020

  • These non-invasive imaging techniques help identify vascular compression and rule out other HFS etiologies.