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Updated: Jun 28, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Predictors of short-term outcomes following endoscopic pituitary surgery
Abtin Tabaee1, Vijay K Anand, Yolanda Barrón
1Department of Otolaryngology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10003, USA. atabaee@hotmail.com
Objective:
Refinement of endoscopic pituitary surgery requires an understanding of the impact of demographic and surgical variables on outcomes.
Methods:
Multivariate logistic regression and ANOVA models were used to explore variables for association with outcomes in a consecutive series of 57 patients undergoing endoscopic pituitary surgery.
Results:
The mean duration of surgery was 177 min and was longer in patients with larger tumor size (p=0.03) and presentation with visual symptoms (p=0.02) in univariate analyses. The median duration of hospitalization was 3 days and was longer in patients with larger tumors (p=0.0005). Gross tumor removal was achieved in 89%. Tumor size correlated with extent of tumor removal with an almost 3-fold decrease in complete tumor removal for every 1cm increase in tumor size (p=0.047). High rates of hormonal control (90%) and improvement in visual symptoms (92%) were noted.
Conclusions:
High rates of gross tumor removal, hormonal cure and visual field improvement were noted in this series. Markers including tumor size and visual symptoms may be used to stratify patients.
