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Updated: Jun 28, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

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Published on: June 26, 2020

Neuralgic amyotrophy associated with hepatitis E virus.

Farina Fong¹, Memon Illahi

¹farina@doctors.org.uk

Clinical Neurology and Neurosurgery

|November 7, 2008

Summary

This summary is machine-generated.

Hepatitis E infection may cause neuralgic amyotrophy (NA), a condition causing neuropathic pain and limb weakness. This case report highlights a potential new trigger for NA, suggesting an immune response.

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Area of Science:

Neurology
Infectious Diseases
Hepatology

Background:

Neuralgic amyotrophy (NA) presents with neuropathic pain and paresis, often affecting the brachial plexus.
Known triggers for NA include trauma, surgery, pregnancy, inoculations, and infections, though the exact cause remains elusive.
Previous reports noted liver enzyme derangements in NA patients without identifying a cause.

Observation:

A 53-year-old male presented with bilateral NA, peripheral neuropathy, and isolated liver enzyme abnormalities.
Serological testing confirmed hepatitis E infection.
Other common NA-associated infections were ruled out.

Findings:

Electrophysiological studies supported the diagnosis of NA.
This case links hepatitis E infection to the development of NA.
Hepatitis E is identified as a potential novel cause of neuralgic amyotrophy.

Implications:

The findings suggest hepatitis E as a potential precipitating factor for NA.
This supports the hypothesis of an immune-mediated pathogenesis in NA.
Further research is warranted to explore the link between hepatitis E and NA.