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Updated: Jun 28, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

Imidazole pyrimidine amides as potent, orally bioavailable cyclin-dependent kinase inhibitors

Clifford D Jones1, David M Andrews, Andrew J Barker

  • 1Cancer and Infection Research, AstraZeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK. cliff.jones@astrazeneca.com

Bioorganic & Medicinal Chemistry Letters
|November 7, 2008
PubMed

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