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Related Experiment Video

Updated: Jun 28, 2026

Sleeve Gastrectomy in Mice using Surgical Clips

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Bariatric surgery: risks and rewards.

Walter J Pories¹

¹East Carolina University, Greenville, North Carolina 27834, USA. pories@aol.com

The Journal of Clinical Endocrinology and Metabolism

|December 4, 2008

Summary

This summary is machine-generated.

Bariatric surgery offers a safe and effective solution for severe obesity, leading to significant weight loss and remission of related health conditions like type 2 diabetes. It is the recommended treatment for individuals with a body mass index over 35.

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Area of Science:

Bariatric Surgery
Obesity Medicine
Metabolic Surgery

Background:

Severe obesity affects over 23 million Americans, with body mass index (BMI) exceeding 35.
Obesity is linked to serious comorbidities including diabetes, hypertension, and cardiopulmonary failure.

Purpose of the Study:

To examine the effectiveness of bariatric surgery in managing severe obesity and its associated comorbidities.
To assess the safety and outcomes of various bariatric surgical procedures.

Main Methods:

Review of outcomes for adjustable gastric banding, gastric bypass, and biliopancreatic bypass with duodenal switch.
Inclusion of investigational procedures, complication reviews, and patient selection criteria.
Analysis of evidence from controlled randomized studies.

Main Results:

Bariatric surgery achieves durable weight loss exceeding 100 lb (46 kg).
Over 80% of patients experience long-term remission of type 2 diabetes.
Surgery leads to significant reductions in comorbidities and all-cause mortality with a 90-day mortality rate of 0.35% in Centers of Excellence.

Conclusions:

Bariatric surgery is the preferred treatment for severe obesity.
It provides substantial benefits for weight control and comorbid conditions.