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Updated: Jun 28, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
"Hybrid" stent delivery in the pulmonary circulation
Ralf J Holzer1, Joanne L Chisolm, Sharon L Hill
1The Heart Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. Ralf.Holzer@NationwideChildrens.org
Hybrid intraoperative stent therapy for pulmonary artery stenoses is safe and effective, with successful deployment in 90% of cases. This approach, utilizing direct vision or vascular puncture, offers a viable treatment option for complex PA stenoses.
Area of Science:
- Cardiology
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Pulmonary artery (PA) stenoses are treatable with surgical patch angioplasty, transcatheter stenting, and intraoperative stent delivery.
- Hybrid intraoperative therapy for PA stenoses has gained traction with advancements in techniques and equipment.
Purpose of the Study:
- To describe the institutional experience with hybrid intraoperative stent therapy for pulmonary artery (PA) stenoses.
- To evaluate the safety and effectiveness of this hybrid approach in a pediatric patient cohort.
Main Methods:
- Retrospective review of 20 patients (median age 5.1 years) who underwent hybrid PA stent therapy between March 2003 and April 2008.
- Analysis of stent implantation methods (direct vision, vascular puncture, or combined) and patient outcomes.
- Inclusion of patients with complex congenital heart disease, including tetralogy of Fallot, PA with VSD, and truncus arteriosus.
Main Results:
- Successful stent deployment was achieved in 18/20 (90%) procedures.
- Adverse events occurred in 3/20 (15%) procedures, including two unsuccessful stent deliveries (malposition and fracture).
- Median follow-up was 1.7 years, with 35% of patients requiring re-intervention at the stent site.
Conclusions:
- Hybrid stent delivery in the operating room, via direct vision or vascular puncture, is a safe and effective treatment for PA stenoses.
- A well-equipped hybrid operating suite supports safe intraoperative stent delivery across diverse patient populations.
- Effective collaboration between surgical and interventional teams is crucial for successful outcomes.
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