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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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Related Experiment Video

Updated: Jun 28, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

[Rheumatic diseases in pregnancy].

E Märker-Hermann1, H Bauer, E Gromnica-Ihle

  • 1Klinik Innere Medizin IV (Rheumatologie, klinische Immunologie und Nephrologie), HSK Dr. Horst Schmidt Klinik GmbH, Wiesbaden. Elisabeth.Maerker-Hermann@HSK-Wiesbaden.de

Deutsche Medizinische Wochenschrift (1946)
|November 7, 2008
PubMed
Summary
This summary is machine-generated.

Pregnancy can affect rheumatic disease activity, and vice versa. Careful adaptation of antirheumatic drug therapy is crucial during pregnancy and breastfeeding for maternal and fetal health.

Related Experiment Videos

Last Updated: Jun 28, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Area of Science:

  • Rheumatology and Immunology
  • Reproductive Health
  • Perinatology

Background:

  • Rheumatic diseases significantly impact reproductive outcomes, pregnancy progression, and fetal development.
  • Disease activity in inflammatory rheumatic conditions can fluctuate during pregnancy, showing periods of remission or exacerbation.
  • Specific conditions like rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and systemic lupus erythematosus serve as key examples.

Purpose of the Study:

  • To elucidate the complex interplay between rheumatic diseases and pregnancy.
  • To examine how pregnancy influences the course of various inflammatory rheumatic diseases.
  • To highlight the critical considerations for antirheumatic medication management in pregnant and breastfeeding individuals.

Main Methods:

  • Review and synthesis of existing literature on rheumatic diseases in pregnancy.
  • Case illustrations of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and systemic lupus erythematosus.
  • Analysis of therapeutic strategies for antirheumatic drugs during gestation and lactation.

Main Results:

  • Rheumatic diseases present unique challenges and considerations throughout pregnancy.
  • Pregnancy can lead to modifications in the clinical presentation and activity of rheumatic conditions.
  • Management of antirheumatic therapies requires careful, individualized adjustments.

Conclusions:

  • Understanding the bidirectional relationship between rheumatic diseases and pregnancy is essential for optimal patient care.
  • Antirheumatic drug selection and dosing must be critically evaluated and adapted for pregnant and breastfeeding women.
  • Multidisciplinary management is key to improving outcomes for mothers and infants affected by rheumatic diseases.