Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Microbial Bioremediation of Plastics01:28

Microbial Bioremediation of Plastics

Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of sodium nitroprusside on the default mode network of patients with schizophrenia and healthy controls.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)·2025
Same author

Impact of D-Amino Acids in Schizophrenia.

Biomolecules·2025
Same author

Immunometabolism perturbations in post-COVID-19 condition: interleukin-6 and monoamine oxidase interactions drive neuropsychiatric syndromes.

Brain, behavior, and immunity·2025
Same author

Variation in the osmotic characteristics of aging red blood cells: insights for cryopreservation optimization.

Cytotherapy·2025
Same author

Women and People From Deprived Areas Are Less Likely to be Assessed for Liver Transplantation for Alcohol-related Liver Disease: Results From a National Study of Transplant Assessments.

Transplantation direct·2025
Same author

The Role of Neuroglia in the Development and Progression of Schizophrenia.

Biomolecules·2025

Related Experiment Video

Updated: Jun 28, 2026

Isolation of Native Soil Microorganisms with Potential for Breaking Down Biodegradable Plastic Mulch Films Used in Agriculture
13:38

Isolation of Native Soil Microorganisms with Potential for Breaking Down Biodegradable Plastic Mulch Films Used in Agriculture

Published on: May 10, 2013

Bioactive contaminants leach from disposable laboratory plasticware.

G Reid McDonald1, Alan L Hudson, Susan M J Dunn

  • 1Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2B7, Canada.

Science (New York, N.Y.)
|November 8, 2008
PubMed
Summary

Chemicals leach from disposable lab plasticware, affecting protein function and bioassay results. This impacts the reliability of biological research using common lab supplies.

More Related Videos

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

Related Experiment Videos

Last Updated: Jun 28, 2026

Isolation of Native Soil Microorganisms with Potential for Breaking Down Biodegradable Plastic Mulch Films Used in Agriculture
13:38

Isolation of Native Soil Microorganisms with Potential for Breaking Down Biodegradable Plastic Mulch Films Used in Agriculture

Published on: May 10, 2013

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

Area of Science:

  • Biochemistry
  • Materials Science
  • Laboratory Practices

Background:

  • Disposable plasticware is essential in biological research labs.
  • Plastic manufacturing involves additives for stability and performance.
  • Some additives, like slip agents and biocides, have biological activity.

Purpose of the Study:

  • To investigate the leaching of manufacturing agents from disposable plasticware.
  • To assess the impact of leached agents on protein function and bioassays.

Main Methods:

  • Analysis of leaching from common plastic labware into various solvents.
  • Testing the effects of leached substances on protein behavior and bioassay outcomes.

Main Results:

  • Manufacturing agents demonstrably leach from plasticware into buffers, DMSO, and methanol.
  • Leached chemicals significantly alter protein structure and function.
  • Bioassay results are profoundly affected by these contaminants.

Conclusions:

  • Leaching of manufacturing agents from disposable plasticware poses a significant risk to research integrity.
  • Findings necessitate a re-evaluation of disposable plasticware use in biological research.
  • Awareness and mitigation strategies are crucial for reliable experimental outcomes.