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Updated: Jun 28, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Effective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma
Yoshimasa Maniwa1, Masahiro Yoshimura, Masahiko Takata
1Divisions of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Abstract:
Malignant pleural mesothelioma (MPM) is an aggressive and fatal tumor of the pleura and its incidence has been increasing as a result of the widespread use of asbestos worldwide. Numerous chemotherapeutic agents have been tested in many clinical trials, but the response rate does not exceed 20% for most of the investigated regimens. Here we report a case of MPM in which the chemotherapy based on the chemosensitivity test was very effective on palliation with stable disease for a long time.
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