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Updated: Jun 28, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Circadian incidence of non-inflammatory retinal artery occlusions
Dieter Schmidt1, Martin Schumacher, Nicolas Feltgen
1Department of Ophthalmology, University of Freiburg, Freiburg, Germany.
Background And Purpose:
Myocardial infarction and stroke tend to occur in the morning. We were interested in discovering when the onset of visual loss occurred in patients with retinal artery occlusion (RAO). Assuming that the therapeutic time slot is about 2 to 6 hours, a cumulated incidence during the night might have therapeutic implications.
Methods:
We retrospectively evaluated the data of 266 patients (175 male and 91 female patients) with non-inflammatory RAO: 211 patients with central retinal artery occlusion (CRAO), 36 patients with branch retinal artery occlusion (BRAO), and 19 patients with hemi-central retinal artery occlusion (hemi-CRAO).
Results:
Nocturnal visual loss occurred in 25 patients (9.4%). Ocular deterioration during the day was recorded in 173 patients (65.1%). Visual loss at waking was recorded in 59 patients (22.2%). In most patients with short-term latency (
Conclusions:
Visual loss due to ocular arterial occlusions can occur at any time. Visual deterioration has been recorded more often during the day than during the night.
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