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Related Concept Videos

Size-Exclusion Chromatography01:08

Size-Exclusion Chromatography

In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Molecular Shapes01:18

Molecular Shapes

Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.Two regions of electron density in a diatomic...
Molecular and Ionic Solids02:54

Molecular and Ionic Solids

Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
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Pore Transport and Ion-Pair Transport01:17

Pore Transport and Ion-Pair Transport

Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct microscopic...

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Updated: Jun 28, 2026

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
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Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Published on: April 17, 2012

Molecular sieves in medicine.

Marek Danilczuk1, Karolina Długopolska, Tomasz Ruman

  • 1Institute of Nuclear Chemistry and Technology, Dorodna, Warsaw, Poland. danilcma@udmercy.edu

Mini Reviews in Medicinal Chemistry
|November 11, 2008
PubMed
Summary

Microporous and mesoporous materials, like zeolites, show promise in medicine. These molecular sieves are explored for drug delivery, cancer therapy, and antimicrobial uses due to their biological stability.

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Porous Silicon Microparticles for Delivery of siRNA Therapeutics

Published on: January 15, 2015

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Microporous and mesoporous materials exhibit favorable biological properties and stability.
  • Zeolites, a type of molecular sieve, have garnered attention for diverse medical applications.

Purpose of the Study:

  • To provide a concise overview of the medical applications of molecular sieves.
  • To highlight the potential of zeolites in various therapeutic and diagnostic contexts.

Main Methods:

  • Literature review of studies on microporous and mesoporous materials in medicine.
  • Analysis of research focusing on zeolite applications in drug delivery, cancer therapy, and antimicrobial treatments.

Main Results:

  • Zeolites are investigated as effective drug carriers.
  • Their role as adjuvants in anticancer therapy and as antimicrobial agents is under examination.
  • Potential use as dietetic supplements is also explored.

Conclusions:

  • Molecular sieves, particularly zeolites, possess significant potential for medical applications.
  • Further research is warranted to fully exploit their therapeutic and diagnostic capabilities in the biomedical field.