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Updated: Jun 28, 2026
11:17
Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
Low molecular weight heparins as antineoplastic agents
1Cattedra ed U.O. di Ematologia con trapianto, Azienda Ospedaliera Universitaria Policlinico P. Giaccone, via del Vespro 127, I-90127, Palermo, Italy. sergio.siragusa@unipa.it
Recent Patents on Anti-Cancer Drug Discovery
|November 11, 2008
Summary
Low molecular weight heparins (LMWHs) show promise in managing cancer patients by preventing and treating blood clots. Emerging evidence suggests LMWHs may also improve survival through anticancer effects.
Area of Science:
- Oncology
- Hematology
- Pharmacology
Background:
- Cancer patients frequently experience venous thromboembolism (VTE).
- Low molecular weight heparins (LMWHs) are established anticoagulants for VTE prevention and treatment.
- Recent studies suggest LMWHs might possess direct anticancer properties.
Purpose of the Study:
- To review recent findings on the role of LMWHs in cancer patient management.
- To explore the potential antineoplastic effects of LMWHs.
- To discuss recent patents related to LMWHs in oncology.
Main Methods:
- Literature review of recent studies.
- Analysis of clinical trial data.
- Examination of patent filings.
Main Results:
- LMWHs are effective in VTE prophylaxis and treatment in cancer patients.
- Preliminary data indicate LMWHs may improve survival rates in certain cancers.
- Ongoing research is exploring the mechanisms of LMWH's antineoplastic activity.
Conclusions:
- LMWHs offer a dual benefit in cancer care: VTE management and potential survival improvement.
- Further research is warranted to elucidate the antineoplastic mechanisms and clinical utility of LMWHs in oncology.
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