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Dextromethorphan.
Joseph A Banken1, Howell Foster
1College of Medicine, Department of Obstetrics and Gynecology, Antenatal and Neonatal Guidelines, Education and Learning System (ANGELS), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. BankenJosephA@uams.edu
Annals of the New York Academy of Sciences
|November 11, 2008
Summary
Dextromethorphan (DXM) is increasingly abused, especially in rural areas. This review examines DXM abuse trends using national and poison control center data, highlighting its emerging role as a drug of abuse.
Area of Science:
- Pharmacology
- Toxicology
- Public Health
Background:
- Dextromethorphan (DXM) is an over-the-counter cough suppressant.
- Emerging evidence suggests widespread abuse of DXM in various formulations.
- Co-ingredients in over-the-counter (OTC) products may contribute to adverse effects.
Purpose of the Study:
- To review the role of dextromethorphan as an emerging drug of abuse.
- To discuss the effects of dextromethorphan and its co-ingredients.
- To explore national trends and implications of DXM abuse.
Main Methods:
- Analysis of Drug Abuse and Warning Network (DAWN) national data.
- Examination of data from poison control centers, including the Arkansas Poison Control Center (APCC).
- Postulation of possible national trends in dextromethorphan abuse.
Main Results:
- Dextromethorphan abuse is an emerging trend.
- Data from APCC indicate a particular rise in abuse within a rural US area.
- Abuse involves dextromethorphan and potentially other ingredients in OTC formulations.
Conclusions:
- Dextromethorphan represents a growing public health concern due to its abuse potential.
- Poison control center data are crucial for identifying and monitoring emerging drug abuse trends.
- Further research and public health interventions are needed to address dextromethorphan abuse.
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