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Nuclear localization of SNARK; its impact on gene expression

Wataru Kuga1, Katsuya Tsuchihara, Tsutomu Ogura

  • 1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561, Japan.

Biochemical and Biophysical Research Communications
|November 11, 2008
PubMed
Summary

SNARK, a kinase involved in stress response, primarily localizes to the nucleus. This nuclear localization, mediated by a specific signal, is crucial for SNARK's role in regulating gene expression during cellular stress.

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