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Updated: Jun 28, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
Published on: May 16, 2021
Drug discovery: new models for industry-academic partnerships
Cathy J Tralau-Stewart1, Colin A Wyatt, Dominique E Kleyn
1Drug Discovery Centre and Business Development, Imperial College London SW7 2AZ, UK. c.tralau@imperial.ac.uk
Abstract:
The re-focusing of pharmaceutical industry research away from early discovery activities is stimulating the development of novel models of drug discovery, notably involving academia as a 'front end'. In this article the authors explore the drivers of change, the role of new entrants (universities with specialised core facilities) and novel partnership models. If they are to be sustainable and deliver, these new models must be flexible and properly funded by industry or public funding, rewarding all partners for contributions. The introduction of an industry-like process and experienced management teams signals a revolution in discovery that benefits society by improving the value gained from publicly funded research.
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