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Novel horseradish peroxidase substrates for use in immunohistochemistry

Kenneth H Petersen1

  • 1Dako A/S, Produktionsvej 42, DK-2600 Glostrup, Denmark. Kenneth.Petersen@dako.com

Journal of Immunological Methods
|November 11, 2008
PubMed

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Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...