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Updated: Jun 28, 2026

Curtain Flow Column: Optimization of Efficiency and Sensitivity
Published on: June 12, 2016
Fundamental mathematical relationships for retention volumes in liquid chromatography
Mei Wang1, Jennifer Mallette, Jon F Parcher
1Chemistry Department, University of Mississippi, University, MS 38677, USA.
Abstract:
Various issues currently impeding elucidation of the retention mechanism(s) in reversed-phase liquid chromatography are discussed. A generalized derivation of the retention volume equations for both concentration and tracer pulse chromatography are presented. The derivations follow the general direction of multiple, ad hoc derivations presented in the extant literature. The retention volume equations derived herein represent a body of work previously dispersed throughout the chromatographic literature.
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