Related Experiment Video
Updated: Jun 28, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
Type 1 diabetes and idiopathic retroperitoneal fibrosis: case report
1Pôle NUDE, service d'endocrinologie, diabète et maladies métaboliques, hôpitaux universitaires de Strasbourg, 67091 Strasbourg cedex, France.
Abstract:
Retroperitoneal fibrosis is characterized by the presence of a retroperitoneal tissue, consisting of chronic inflammation and marked fibrosis, which entraps the retroperitoneal organs. In two-thirds of cases, the retroperitoneal fibrosis is idiopathic. The pathogenic mechanism is not clearly identified. We report a case of idiopathic retroperitoneal fibrosis associated with type 1 diabetes mellitus. A 61-year-old woman with C peptide negative insulindependent diabetes developed retroperitoneal fibrosis revealed by bilateral hydronephrosis. Anti-GAD 65 antibodies were positive. There were no signs of autoimmune pancreatitis: no steatorrhea, normal IgG4 isotype levels, and absence of pancreas morphological abnormalities.
Related Concept Videos
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes III: Clinical Manifestations
Type II Diabetes I: Introduction
Type II Diabetes II: Pathophysiology

