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Related Concept Videos

iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Blood Transfusion and Agglutination02:45

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
Blood Transfusion01:15

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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Updated: Jun 28, 2026

Efficient iPS Cell Generation from Blood Using Episomes and HDAC Inhibitors
08:14

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Published on: October 28, 2014

Autologous blood programs: what is happening?

G Rock1, R Berger, D Filion

  • 1Department of Pathology, The University of Ottawa, Canadian Apheresis Group, Suite 199, 435 St. Laurent Boulevard, Ottawa, Ontario, Canada K1K 2Z8. cag@ca.inter.net

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|November 11, 2008
PubMed
Summary

Autologous blood programs in Ontario show significant variability in service provision and integration with Canadian Blood Services (CBS). This contrasts with standardized whole blood and apheresis collections, highlighting a need for greater consistency in autologous blood services.

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Area of Science:

  • Transfusion Medicine
  • Healthcare Management

Background:

  • Preoperative autologous blood collection has gained prominence, particularly post-AIDS epidemic.
  • Despite increased application, autologous blood programs face both praise and criticism, with limited data on their actual implementation.

Purpose of the Study:

  • To assess the demographics, logistics, and funding of autologous blood programs in Ontario's largest hospitals.
  • To identify variations in autologous blood service availability and operation across the province.

Main Methods:

  • A survey was distributed to 155 large hospitals in Ontario.
  • 78 hospitals responded, providing data on their autologous blood program access, structure, and funding.

Main Results:

  • 77 of 78 responding hospitals had access to an autologous program.
  • 26 hospitals had in-house programs, while 62 utilized Canadian Blood Services (CBS).
  • 15 hospitals lacked any autologous program access; some programs were funded by patient fees.

Conclusions:

  • Autologous blood programs in Ontario exhibit considerable variability, with some regions lacking services while others have active programs.
  • This variability contrasts sharply with the standardized approach to whole blood and apheresis collections managed by CBS.
  • There is a notable lack of standardization in autologous blood collection services across Canadian provinces.