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Related Experiment Video

Updated: Jun 28, 2026

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Published on: April 1, 2022

Breast carcinoma during pregnancy.

Gamal A Khairy¹, Huda A Al-Abdulkarim

¹Department of Surgery College of Medicine, King Khalid University Hospital, PO Box 7805 Riyadh 11472, Kingdom of Saudi Arabia. gkhairy@ksu.edu.sa

Saudi Medical Journal

|November 11, 2008

Summary

Pregnancy-associated breast cancer is rare but often diagnosed at advanced stages. Early detection through prenatal breast exams is crucial for better outcomes in pregnant patients.

Area of Science:

Oncology
Obstetrics & Gynecology
Medical Diagnostics

Background:

Pregnancy-associated breast cancer (PABC) is a rare but aggressive condition.
Early detection and diagnosis of PABC are challenging due to physiological breast changes during pregnancy.

Observation:

A retrospective review of 5 PABC cases over 5 years revealed a prevalence of 2.27%.
Patients presented at a median age of 33 years, with diagnoses occurring as early as the sixth gestational week.
The majority of cases (3/5) were diagnosed at Stage IIIA, with extensive lymph node involvement (≥6 positive nodes) and Grade III disease.

Findings:

Despite early detection in pregnancy, PABC patients frequently present with advanced disease.
The advanced stage at diagnosis mirrors that of non-pregnant women in the region, suggesting PABC may be an overlooked condition exacerbated by pregnancy.

Related Experiment Videos

Last Updated: Jun 28, 2026

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Published on: April 1, 2022

Implications:

Obstetricians should incorporate thorough breast examinations into routine prenatal care.
Prompt referral of any suspicious breast findings during pregnancy is essential for timely diagnosis and treatment.
Increased awareness and screening can improve outcomes for PABC patients.