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Published on: April 1, 2022
Breast carcinoma during pregnancy.
Gamal A Khairy1, Huda A Al-Abdulkarim
1Department of Surgery College of Medicine, King Khalid University Hospital, PO Box 7805 Riyadh 11472, Kingdom of Saudi Arabia. gkhairy@ksu.edu.sa
Saudi Medical Journal
|November 11, 2008
Summary
Pregnancy-associated breast cancer is rare but often diagnosed at advanced stages. Early detection through prenatal breast exams is crucial for better outcomes in pregnant patients.
Area of Science:
- Oncology
- Obstetrics & Gynecology
- Medical Diagnostics
Background:
- Pregnancy-associated breast cancer (PABC) is a rare but aggressive condition.
- Early detection and diagnosis of PABC are challenging due to physiological breast changes during pregnancy.
Observation:
- A retrospective review of 5 PABC cases over 5 years revealed a prevalence of 2.27%.
- Patients presented at a median age of 33 years, with diagnoses occurring as early as the sixth gestational week.
- The majority of cases (3/5) were diagnosed at Stage IIIA, with extensive lymph node involvement (≥6 positive nodes) and Grade III disease.
Findings:
- Despite early detection in pregnancy, PABC patients frequently present with advanced disease.
- The advanced stage at diagnosis mirrors that of non-pregnant women in the region, suggesting PABC may be an overlooked condition exacerbated by pregnancy.
Implications:
- Obstetricians should incorporate thorough breast examinations into routine prenatal care.
- Prompt referral of any suspicious breast findings during pregnancy is essential for timely diagnosis and treatment.
- Increased awareness and screening can improve outcomes for PABC patients.
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