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A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
Published on: May 9, 2016
Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments
Franz Chouly1, Annemie Van Hirtum, Pierre-Yves Lagrée
1INRIA, REO Team, Rocquencourt, BP 105, 78153 Le Chesnay Cedex, France. franz.chouly@inria.fr
Abstract:
In the presented study, a numerical model which predicts the flow-induced collapse within the pharyngeal airway is validated using in vitro measurements. Theoretical simplifications were considered to limit the computation time. Systematic comparisons between simulations and measurements were performed on an in vitro replica, which reflects asymmetries of the geometry and of the tissue properties at the base of the tongue and in pathological conditions (strong initial obstruction). First, partial obstruction is observed and predicted. Moreover, the prediction accuracy of the numerical model is of 4.2% concerning the deformation (mean quadratic error on the constriction area). It shows the ability of the assumptions and method to predict accurately and quickly a fluid-structure interaction.
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